Axis 2 : Respiratory fungal infections in cystic fibrosis

The main challenges in this area are to identify the pathogenic mechanisms of fungi and characterise the processes that enable them to adapt to the microenvironments they encounter in the airways of cystic fibrosis patients. 

Below are a few examples of achievements or projects in this area: 

Response of human macrophages against Scedosporium apiospermum and Scedosporium dehoogii.

Microbiota and fungibacterial interactions in cystic fibrosis lung.

Structure and distribution of histidine kinase receptors in the fungal kingdom.

Oxidative stress response pathways in fungi.

Fungal colonisation of the airways of cystic fibrosis patients: the role of environmental reservoirs.

Updated guide to the processing of respiratory tract samples from cystic fibrosis patients.